Clinical trials for antidepressants do not use representative participants!

[LiaAtha]

They also found that patients with OCD are also usually excluded.

[Alora]

Thank you for that one. Look at what Dr. Wisniewski and colleagues found:

* Response rates: 51.6% in the efficacy sample (those who are representative group), 39.1% in the nonefficacy sample
* Remission rate: 34.4% in the efficacy sample, 24.7% in the nonefficacy sample

[markedman]

This is not the first time I've heard of this. I know that a majority of depressed patients have been excluded from clinical trials of antidepressants.

[julie20099]

To assess depression markers (symptoms and antidepressant medicine use) in Diabetes Prevention Program (DPP) participants and to determine whether changes in depression markers during the course of the study were associated with treatment arm, weight change, physical activity level, or participant demographic characteristics.

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